so i am several months in to using the GUIX System as my daily driver operating system on both my main terminal and laptop.
apart from having to enable some non-free drivers in order to get the wireless (on laptop) and graphics card (on terminal) working, i have had absolutely no issues with it. it is rock solid.
i highly recommend this highly-LISP-orientated operating system.
i have also played more games on ‘Linux’ on GUIX than i have ever played before. the support that this system has for reproducible builds for video games is very, very good.